| Lectures: 4 Periods/Week | Sessional Marks: 30 |
| University Exam: 3 Hours | University Examination Marks: 70 |
UNIT-I
An overview of industrial bio chemical processes and comparing with chemical processes.
Industrially important microbial strains, their structure and classification.
Chemicals of life: Lipids, proteins, building blocks of DNA and RNA.
UNIT-II
The kinetics of enzyme-catalyzed reactions: The enzyme substrate complex, Michaelis-Menten kinetics, enzyme inhibition, other factors affecting on enzyme activity-pH and temperature.
Applied enzyme catalysis: Applications of enzymes, enzyme immobilization, immobilized enzyme kinetics, Transport across cell membranes.
UNIT-III
The kinetics of cell cultures: Monod growth kinetics, growth cycle phases for batch cultivation.
Bio reactors: Ideal batch rector, fed batch reactor, enzyme-catalyzed reactions in CSTRs, CSTR reactors with recycle, plug flow reactor, Immobilised and free cell reactors.
Multiphase Bio reactors: Packed bed reactors, fluidized bed bio reactors, trickle bed reactors, sterilization, fermentation technology, scale up and scale down concepts.
UNIT-IV
Product recovery operations: Recovery of particulates - Filtration, centrifugation, sedimentation.
Production Isolation: Extraction, precipitation, membrane separations. Purification -Chromatographic techniques. Final production isolation, Drying and crystallization.
Text Books