| Lectures/tutorials: 4+1 Periods/Week | Sessional Marks: 30 |
| University Exam: 3 Hours | University Examination Marks: 70 |
UNIT-I
Structure and Properties:
Elemental Analysis Qualitative and Quantitative, Empirical and molecular formula determination, Problems based on Molecular and Empirical formula determinations.
Elemental Analysis Qualitative and Quantitative, Empirical and molecular formula determination, Problems based on Molecular and Empirical formula determinations.
Electron Displacements in a molecule:
Inductive, mesomeric and electromeric effects, resonance, hyper conjugation, Reaction mechanisms of SN1, SN2, E1, and E2 reactions, Free
radical, cationic & anionic polymerization, Zigler-natta polymerization, hydrogen bonding in organic molecules and its effect.
Stereo Chemistry:
Basics of optical and geometrical isomerisms - Enantiomers, Diastereoisomers, Meso compounds, sequence rules, 'R' and 'S', E&Z configuration,
Keto-enol tautomerism.
UNIT-II
Alkanes:
Classification by structure, conformations of Ethane and n-butane. Preparation methods - Wurtz reaction, Kolbes electrolytic method.
Halogenation in alkanes (alkyl halides) - Free radical substitution method.
Cyclo alkanes:
Stability of cyclo alkanes, Bayers strain theory, conformation analysis of cyclo hexane and di-substituted cyclo hexanes.
Alkenes:
Preparation by de-hydration of alcohols, de-hydro halogenation of alkyl halides (Saytzeff rule). Addition reactions. Markownikoff's and Anti
Markownikoff's rule. 1,2 and 1, 4 additions in dienes.
Benzene:
Aromaticity, Huckels rule, Electrophilic aromatic substitution, Mechanism of Nitration, Friedel-Crafts alkylation and acylation - Orientation
in disubstituted benzenes, activating and deactivating groups, aryl halides, aralkyl halides.
UNIT-III
Heterocyclic compounds:
Furan, Thiphene, Pyrrole, Pyridine, Indole, their important derivatives.
Hydroxy compounds:
Manufacture of alcohol from molasses, Phenols: acidity comparison with alcohol. Reactions of phenol - Riemer Tiemann reaction, Kolbe's reaction,
Fries re-arrangement.
Carbonyl compounds:
Aldehydes and ketones-Preparation-Grignards reagent, Gatterman, Koch reaction. Nucleophilic addition reactions of carbonyl compounds,
Cannizzaro reaction, aldol condensation, Perkin, Reformatsky, Claisen condensation, Clemmenson reduction, Wolfkishner reduction,
Pinacol-Pinacolone rearrangement, Tishenko reaction, Haloform reaction, Benzoin condensation.
UNIT-IV
Carboxylic acids:
Acidity, influence of substitutents on acidity, functional derivatives of carboxylic acids - acid halides, amides, anhydrides, esters.
Aliphatic and Aromatic amines:
1o, 2o, 3o amines - distinguishing tests, preparation by Hofmann's degradation of amides, basicity of amines, diazonium salts, preparation and
synthetic importance - sand mayer reaction.
Biomolecules:
Nomenclature, classification of Carbohydrates, Proteins & Lipids, structure and general reactions of glucose and fructose and their inter
conversions, muta rotation.
Text Books